Well, I can say one thing: I've never seen a movie quite like this one. It is one of the more bizarre movies I've seen. Mostly animated, it shows the world inside Frank's body consisting of the huge civilization (portrayed as a city) with the cells being the citizens. Inside Frank, the story centers around Osmosis Jones, a while blood cell.
I will say this: Frank was one of the most gross, sickening human beings I've seen in a movie. He was an ultra-slob whose only purpose in life seemed to be to eat junk food all the time and not shave and look slobby. You'd think if they were going to make a movie about the inside of someone, they'd have picked someone better looking with more of a life, that the movie viewers would actually care about.
I found the portrayal of life inside the huge city of Frank's body to be quite interesting. I'd certainly never thought about cells inside a body as citizens in a self-contained city. Warner Brothers could use this idea to make some excellent educational programs explaining how different parts of the body work and interact using characters and depictions like the ones used in the movie. Such an approach, done in the correct manner, would have entertainment and educational values for elementary school children.
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Evans A Criswell
Huntsville-Decatur Movie Theatre Information Site